Vonoprazan伏诺拉生
反流性食管炎、胃溃疡;与抗生素联用根除幽门螺杆菌
- CAS 号
- 881681-00-1
- 治疗领域
- 消化 / 幽门螺杆菌
- 靶点 / 机制
- ATP4A·ATP4B
- 标示纯度
- 99%+
- 注册就绪度
- GMP/DMF
- 商业化层级
- API(已商业化)
- 关联中间体
- 14 项可配套供应
发布逻辑 · 为什么值得上线
首个上市 P-CAB,抑酸更强更持久,并显著提升幽门螺杆菌根除率;亚太 HP 高发区需求尤为可观。
消化 / 幽门螺杆菌 · 已上市、可即采即用
GMP/DMF 就绪,可支撑目标市场的注册申报与审计
配套 14 项关键中间体,量产与降本可控
产品说明 · Product Description
Vonoprazan is a medication belonging to the potassium-competitive acid blocker (PCAB) class. It is used for treating stomach and duodenal ulcers as well as for eradicating Helicobacter pylori infection when used in combination with antibiotics. Unlike traditional proton-pump inhibitors (PPIs), vonoprazan does not require activation in an acidic environment. It directly and reversibly inhibits the proton pump in gastric parietal cells, leading to a more potent, rapid, and prolonged suppression of gastric acid secretion. This makes it particularly effective for conditions like erosive esophagitis and Helicobacter pylori infection.
供应来源:优贝德 Unibest· Vonoprazan,由优贝德统一对接、审核与交付。治疗领域、适应症与发布逻辑为基于公开药物知识的定性整理; 具体注册可用性与质量指标以 DMF / GMP 文件及订单确认的技术协议为准。